- In eukaryotic cell, the nucleus is the organelle responsible for maintaining the integrity of DNA and for controlling cellular activities such as metabolism, growth, and reproduction by regulating gene expression. It is a double-membraned organelle containing nuclear structures, e.g. chromatin and nuclear bodies. A nuclear body refers to any of the prominent non-membraned structures in the nucleus of the eukaryotic cell.
- Nuclear bodies are prominent structures of non-chromatinic fibrillary material and mostly proteinaceous. Nucleolus, the round granular structure within the nucleus of a cell, composed of proteins, DNA, and RNA, and functions primarily for the creation of ribosomes, is one of the most well-known nuclear structures. Other examples of nuclear bodies are Cajal bodies and gems (Gemini of Cajal bodies), polymorphic interphase karyosomal association (PIKA) domains, promyelocytic leukaemia protein (PML) bodies, splicing speckles, paraspeckles, perichromatin fibrils, and clastosomes.
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