Work House

Author: workhouse123

  • Antineoplastic agents

    Antineoplastic agents

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    Cancer refers to a malignant neoplasm or new growth. Cancer cells manifest uncontrolledproliferation, loss of function due to loss of capacity to differentiate, invasiveness, and the abilityto metastasize.Cancer arises as a result of genetic changes in the cell, the main genetic changes being;inactivation of tumor suppressor genes and activation of oncogenes.There are three approaches for…

  • ANTIVIRAL AGENTS

    ANTIVIRAL AGENTS

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    Viruses are obligate intracellular parasites; their replication depends primarily on syntheticprocesses of the host cell. Viral replication consists of several steps: (1) adsorption to andpenetration into susceptible host cells; (2) uncoating of viral nucleic acid; (3) synthesis of early,regulatory proteins, eg, nucleic acid polymerases; (4) synthesis of RNA/ DNA; (5) synthesis oflate, structural proteins; (6)…

  • ANTIFUNGAL AGENTS

    ANTIFUNGAL AGENTS

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    Fungal infections have increased in incidence and severity in recent years, due to increased inthe use of broad-spectrum antimicrobials and the HIV epidemic. The antifungal drugs fall intotwo groups: antifungal antibiotics and synthetic antifungals.Antifungal antibioticsAmphotericin BAmphotericin B is poorly absorbed from the gastrointestinal tract. Oral amphotericin B is thuseffective only on fungi within the lumen…

  • ANTIMICROBIAL DRUGS

    ANTIMICROBIAL DRUGS

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    Mechanisms of antimicrobial drug action:

  • INTODUCTION

    INTODUCTION

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    Chemotherapy: is the use of chemical agents (either synthetic or natural) to destroy infectiveagents (microorganisms’ i.e bacteria, fungus and viruses, protozoa, and helminthes) and toinhibit the growth of malignant or cancerous cells.Chemotherapeutic agents: are chemical which are intended to be toxic for parasitic cell but nontoxic to the host, such selective toxicity depends on the…

  • ADRENCORTCCAL HORMONES

    ADRENCORTCCAL HORMONES

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    Adenocortical hormones control the metabolism of carbohydrate (CHO), protein, fat and water/electrolytesAdencortical hormones are classified into:a) Glucocorticoid – Cortisone

  • Female Sex Hormones and Hormonal Contraception

    Female Sex Hormones and Hormonal Contraception

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    OestrogensThese drugs can be classified into three groups.

  • OXYTOCICS

    OXYTOCICS

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    Actions: 1. Oxytocin stimulates the uterus and cause physiologic type of contraction

  • Antidiabetogenic drugs

    Antidiabetogenic drugs

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    I. INSULINSources include pork or beef, combination of pork and beef and also human insulin(Recombinant DNA technique)Actions:

  • Introduction

    Introduction

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    Diabetes Mellitus is a disease that occurs as a result of absolute or relative deficiency ofinsulin that results in metabolic and vascular abnormalities.The etiologies include Obesity (because chronic calorie intake and prolonged stimulation of βcell causes a decrease in insulin receptor and also adipose tissue and muscle are lesssensitive),hereditary,damage of pancreatic tissue, diabetogenic hormones(like growth…