Author: workhouse123
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Dose Response relationship
The exact relationship between the dose and the response depends on the biological objectunder observation and the drug employed.When a logarithm of dose as abscissa and responses as ordinate are constructed graphically,the “S” shaped or sigmoid type curve is obtained.The lowest concentration of a drug that elicits a response is minimal dose, and the largestconcentration…
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Pharmacodynamics
Involves how the drugs act on target cells to alter cellular function.A. Receptor and non-receptor mechanisms: Most of the drugs act by interacting with acellular component called receptor. Some drugs act through simple physical or chemicalreactions without interacting with any receptor. Receptors are protein molecules present either on the cell surface or with in the…
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Introduction
Definitions: Pharmacology: Pharmacology is the study of interaction of drugs with living organisms.It also includes history, source, physicochemical properties, dosage forms, methods ofadministration, absorption, distribution mechanism of action, biotransformation,excretion, clinical uses and adverse effects of drugs. Pharmacodynamics: The study of the biological and therapeutic effects of drugs (i.e,“what the drug does to the body”).
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Definitions
Pharmacology: Pharmacology is the study of interaction of drugs with living organisms.It also includes history, source, physicochemical properties, dosage forms, methods ofadministration, absorption, distribution mechanism of action, biotransformation,excretion, clinical uses and adverse effects of drugs.
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The 21st Century: Cutting-Edge Innovations
Pharmacogenomics: Biologics and Biopharmaceuticals: Artificial Intelligence and Drug Discovery:
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The 20th Century: Advancements and Drug Revolution
The Rise of Pharmaceutical Companies: Antibiotics and Chemotherapy: Molecular Biology and Drug Design: Psychopharmacology and Neuroscience:
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The 19th Century: The Birth of Modern Pharmacology
Development of Pharmacodynamics: Synthesis of Drugs:
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The Renaissance to Early Modern Era (16th to 18th Century)
Paracelsus (1493–1541): Advances in Chemistry and Drug Discovery:
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Classical and Medieval Era(500-1500 CE)
Theophrastus (c. 371–287 BCE): Galen (c. 129 – 200 CE): Arab Scholars (8th – 13th Century):