Category: Drugs Action on the Respiratory System

Decongestants are the drugs that reduce congestion of nasal passages, which in turn openclogged nasal passages and enhances drainages of the sinuses.e.g phenylephrine, oxymetazoline etc.Mechanism of ActionMucus membrane decongestants are α1 agonists, which produce localized vasoconstriction onthe small blood vessels of the nasal membrane. Reduce congestion in nasal passages.Clinical uses:Used in congestion associated with rhinitis,…

Cough is a protective reflex, which serves the purpose of expelling sputum and other irritantmaterials from the respiratory airway.Types:

e.g cromolyn sodiumMechanism of actionStabilize the mast cells so that release of histamine and other mediators is inhibitedthrough alteration in the function of delayed chloride channel in cell membrane. It has no roleonce mediator is released and is used for casual prophylaxis.Clinical uses

Drug used in the treatment of bronchia asthma can be grouped into three main categories:

Asthma is physiologically characterized by increased responsiveness of the trachea and bronchito various stimuli and by wide spread narrowing of the airways that changes in severity eitherspontaneously or as a result of therapyImpairment of airflow in bronchial asthma is caused by three bronchial abnormalities.i. Contraction of airway smooth musclesii. Thickening of bronchial mucosa from edema…

The respiratory system includes the upper airway passages, the nasal cavities, pharynx andtrachea as well as the bronchi and bronchioles. Respiration is the exchange of gases betweenthe tissue of the body and to outside environment. It involves breathing in of an air through therespiratory tract, uptake of oxygen from the lungs, transport of oxygen through…