{"id":6591,"date":"2024-11-17T21:20:53","date_gmt":"2024-11-17T21:20:53","guid":{"rendered":"https:\/\/workhouse.sweetdishy.com\/?p=6591"},"modified":"2024-11-17T21:20:54","modified_gmt":"2024-11-17T21:20:54","slug":"mast-cell-stabilizers","status":"publish","type":"post","link":"https:\/\/workhouse.sweetdishy.com\/index.php\/2024\/11\/17\/mast-cell-stabilizers\/","title":{"rendered":"MAST CELL STABILIZERS"},"content":{"rendered":"\n<p>e.g cromolyn sodium<br><strong>Mechanism of action<\/strong><br>Stabilize the mast cells so that release of histamine and other mediators is inhibited<br>through alteration in the function of delayed chloride channel in cell membrane. It has no role<br>once mediator is released and is used for casual prophylaxis.<br><strong>Clinical uses<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Exercise and antigen induced asthma<\/li>\n\n\n\n<li>Occupational asthma<br><strong>Side effects<\/strong><br>Poorly absorbed so minimal side effect<br>Throat irritation, cough, dryness of mouth, chest tightness and wheezing<br><br><strong>TREATMENT OF STATUS ASTHMATICS<\/strong><\/li>\n\n\n\n<li><br><strong>Status asthmatics<\/strong><br>Very sever and sustained attack of asthma which fails to respond to treatment with usual<br>measures<br>Management includes:<\/li>\n\n\n\n<li>Administration of oxygen<\/li>\n\n\n\n<li>Frequent or continuous administration of aerosolized \u00df2 agonists like salbutamol<\/li>\n\n\n\n<li>Systemic corticosteroid like methyl prednisolone or hydrocortisone IV<\/li>\n\n\n\n<li>Aminophylline IV infusion<\/li>\n\n\n\n<li>Iv fluid to avoid dehydration<\/li>\n\n\n\n<li>Antibiotics in the presence of evidence of infection<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>e.g cromolyn sodiumMechanism of actionStabilize the mast cells so that release of histamine and other mediators is inhibitedthrough alteration in the function of delayed chloride channel in cell membrane. It has no roleonce mediator is released and is used for casual prophylaxis.Clinical uses<\/p>\n","protected":false},"author":1,"featured_media":6505,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[693],"tags":[],"class_list":["post-6591","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drugs-action-on-the-respiratory-system"],"jetpack_featured_media_url":"https:\/\/workhouse.sweetdishy.com\/wp-content\/uploads\/2024\/11\/2779928.png","_links":{"self":[{"href":"https:\/\/workhouse.sweetdishy.com\/index.php\/wp-json\/wp\/v2\/posts\/6591","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/workhouse.sweetdishy.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/workhouse.sweetdishy.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/workhouse.sweetdishy.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/workhouse.sweetdishy.com\/index.php\/wp-json\/wp\/v2\/comments?post=6591"}],"version-history":[{"count":1,"href":"https:\/\/workhouse.sweetdishy.com\/index.php\/wp-json\/wp\/v2\/posts\/6591\/revisions"}],"predecessor-version":[{"id":6592,"href":"https:\/\/workhouse.sweetdishy.com\/index.php\/wp-json\/wp\/v2\/posts\/6591\/revisions\/6592"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/workhouse.sweetdishy.com\/index.php\/wp-json\/wp\/v2\/media\/6505"}],"wp:attachment":[{"href":"https:\/\/workhouse.sweetdishy.com\/index.php\/wp-json\/wp\/v2\/media?parent=6591"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/workhouse.sweetdishy.com\/index.php\/wp-json\/wp\/v2\/categories?post=6591"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/workhouse.sweetdishy.com\/index.php\/wp-json\/wp\/v2\/tags?post=6591"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}